Hypofractionated versus conventional radiotherapy with or without chemotherapy in head and neck cancer: A comparative study

Abstract

Background: To investigate tumor response and toxicities in head and neck squamous cell cancer (HNSCC) upon hypofractionated radiotherapy compared with conventional fractionation. Settings and Design: Data from patients with squamous cell cancer of oral cavity, oropharynx, hypopharynx, and larynx (AJCC, 2010 Stage II to IVB); who received hypofractionated (n = 30) or conventionally fractionated (n = 30) radiotherapy, with or without chemotherapy, between January 2010 to June 2011 were retrieved