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Highly Enantioselective Friedel−Crafts Reaction of Indoles with Imines by a Chiral Phosphoric Acid
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Citations
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References
2007
Year
3-Indolyl Methanamine DerivativesEngineeringEnantioselective Friedel−crafts ReactionEnantioselective Friedel−crafts ReactionsOrganic ChemistryCatalysisStereoselective SynthesisChemistryChiral Phosphoric AcidNatural Product SynthesisAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Highly enantioselective Friedel−Crafts reactions of indoles with imines catalyzed by a chiral phosphoric acid are developed, affording the 3-indolyl methanamine derivatives with up to >99% ee for a wide range of substrates.
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