Aspirin inhibits proliferation and induces apoptosis of multiple myeloma cells through regulation of Bcl‐2 and Bax and suppression of <scp>VEGF</scp>

Abstract

ASA exerted antiproliferative and pro-apoptotic action in myeloma cells in vitro and delayed the growth of human myeloma cells in vivo. The underlying mechanisms were ascribed to regulation of Bcl-2 and Bax and suppression of VEGF.