Concepedia

Acceleration of Organic Reactions through Aqueous Solvent Effects

Chemistry - A European Journal · 2005 · 348 citations · 19 references

Concepts

Nonpolar CompoundsChemical EngineeringHigh Hydrostatic PressureEngineeringHydrophobic EffectsHigh PressureHydrogen-bonded LiquidOrganic ChemistryPhysical ChemistryAqueous Solvent EffectsReactivity (Chemistry)ChemistryMolecular KineticsReaction ProcessDeep Eutectic SolventChemical KineticsSolution (Chemistry)

Abstract

The parallels between organic reactions conducted with water as the solvent and reactions conducted under high pressure can be understood in light of theories of aqueous solvation and hydrophobic effects. Such parallels provide powerful tools for promoting reactions of nonpolar compounds.

References

19

“On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension

Sridhar Narayan, John Muldoon, M. G. Finn et al. · Angewandte Chemie International Edition · 2005 · 1.6K citations · Full text

Unique Reactivity, Solvent Extraction, Chemical Engineering +13

Hydrophobic effects on simple organic reactions in water

Ronald Breslow · Accounts of Chemical Research · 1991 · 1.2K citations

Engineering, Altmetric Attention Score, Bibliometrics +16

Practical Approaches to Green Solvents

Joseph M. DeSimone · Science · 2002 · 919 citations

Solvent Extraction, Chemical Engineering, Sustainable Chemical Production +15

Development of Novel Lewis Acid Catalysts for Selective Organic Reactions in Aqueous Media

Shu̅ Kobayashi, Kei Manabe · Accounts of Chemical Research · 2002 · 755 citations

Chemical Engineering, Lewis Acid Catalysts, Selective Organic Reactions +12

Multicomponent Reactions Are Accelerated in Water

Michael C. Pirrung, Koushik Das Sarma · Journal of the American Chemical Society · 2003 · 433 citations

Combinatorial Chemistry, Chemical Engineering, Cross-coupling Reaction +15