Acta Paediatrica · 2015 · 24 citations · 16 references
MedicineDermatologyPediatricsAllergyPediatric DermatologyPediatric EpidemiologyAtopic DermatitisChildhood ObesityInflammatory Skin DisordersAtopic Dermatitis AssociationAtopic Dermatitis PathologyBody Condition IndexChildhood Obesity PrevalenceLogistic RegressionMultinomial RegressionOverweight In ChildhoodPediatric Atopic Dermatitis
AIM: Childhood obesity increases the risk of developing atopic dermatitis, but no objective measuring tool has been used to determine whether it also affects the severity. Our aim was to determine whether an association existed between increased body mass index (BMI) or weight for length and severity of atopic dermatitis, as measured by the SCORing Atopic Dermatitis (SCORAD) index. METHODS: Children with atopic dermatitis who presented to the emergency department at an urban children's hospital (n = 104) were assessed using the SCORAD index. We assessed the relationship between BMI percentile or weight for length percentile, based on age, and atopic dermatitis severity, using single-variable multinomial logistic regression with odds ratios. RESULTS: A significant association was found between BMI >24 and atopic dermatitis severity for children older than 2 years. When analysed separately, a significant association between BMI percentile and SCORAD severity was found in boys but not in girls. CONCLUSION: These data suggest that the severity of atopic dermatitis is associated with increased BMI percentile in children older than 2 years, although this association was not apparent in younger ages using weight for length. Our results indicate the need for new avenues in the prevention and treatment of these entities.
16
Prevalence of Overweight and Obesity in the United States, 1999-2004
Cynthia L. Ogden, Margaret D. Carroll, Lester R. Curtin et al. · JAMA · 2006 · 8.7K citations
Obesity is associated with macrophage accumulation in adipose tissue
Stuart P. Weisberg, Daniel McCann, Manisha Desai et al. · Journal of Clinical Investigation · 2003 · 8.3K citations · Full text
Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
Cynthia L. Ogden, Margaret D. Carroll, Brian K. Kit et al. · JAMA · 2014 · 8.1K citations · Full text