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Synergistic Combination Therapy of 5-Fluorouracil, Vitamin A and Cobalt-60 Radiation upon Head and Neck Tumors
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1978
Year
GliomaVitamin ATriple CombinationNasopharyngeal CancerRadiopharmaceutical TherapyNeck OncologyRadiation OncologyNeck TumorsCancer ResearchRadiologyHealth SciencesRadiation TherapyMedicineRadionuclide TherapyCancer TreatmentPharmacologyCobalt-60 RadiationSynergistic Combination TherapyHead And Neck CancerHead And Neck Squamous Cell CarcinomaFar TherapyOncology
We have applied a triple combination of 5-fluorouracil (5FU), vitamin A and cobalt-60 radiation (FAR therapy) to clinical treatment of head and neck tumors since 1972. The treatment of 33 patients with cancer of larynx and 15 patients with hypopharyngeal or cervical esophageal cancer with FAR therapy during three years from 1972 to 1974 resulted in highly effective synergism in vivo, and the improved points of this therapy were presented.