Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression

High-efficiency transformation of mammalian cells by plasmid DNA.

C Chen, Hiroto Okayama · Molecular and Cellular Biology · 1987 · 5.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

Raphaël Métivier, Graziella Penot, Michael R. Hübner et al. · Cell · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Mutation of the Androgen-Receptor Gene in Metastatic Androgen-Independent Prostate Cancer

Mary‐Ellen Taplin, Glenn J. Bubley, Todd D. Shuster et al. · New England Journal of Medicine · 1995 · 1.3K citations · Full text

Medicine, Genetics, Oncology +17

Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer.

Marika J. Linja, Kimmo Savinainen, Outi R. Saramäki et al. · PubMed · 2001 · 768 citations

Medicine, Molecular Biology, Oncology +14

Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene

Jianming Xu, Yuhong Qiu, Francesco J. DeMayo et al. · Science · 1998 · 690 citations

Life Sciences, Genetics, Molecular Biology +17