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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

Annelies de Klein, Manja Muijtjens, Ronald van Os, Y. Verhoeven, Bep Smit, Antony M. Carr, Alan R. Lehmann, Jan H.J. Hoeijmakers

Current Biology · 2000 · 444 citations · 20 references

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20

Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia

Carrolee Barlow, Shinji Hirotsune, Richard Paylor et al. · Cell · 1996 · 1.5K citations · Full text

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A role for ATR in the DNA damage-induced phosphorylation of p53

Randal S. Tibbetts, Kathryn M. Brumbaugh, Jean Williams et al. · Genes & Development · 1999 · 1.1K citations · Full text

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<i>ATR</i> disruption leads to chromosomal fragmentation and early embryonic lethality

Eric J. Brown, David Baltimore · Genes & Development · 2000 · 944 citations · Full text

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A Suppressor of Two Essential Checkpoint Genes Identifies a Novel Protein that Negatively Affects dNTP Pools

Xiaolan Zhao, Eric G. Muller, Rodney Rothstein · Molecular Cell · 1998 · 739 citations · Full text

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Localization of an ataxia-telangiectasia gene to chromosome 11q22–23

Richard A. Gatti, İzzet Berkel, Elena Boder et al. · Nature · 1988 · 687 citations

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