STIMULATION OF P2y PURINOCEPTORS INDUCES, VIA NITRIC OXIDE PRODUCTION, ENDOTHELIUM-DEPENDENT RELAXATION OF HUMAN ISOLATED CORPUS CAVERNOSUM

Abstract

Human corporal cavernosal strips can be relaxed by stimulation of P2y purinoceptors via NO release. This relaxation is an endothelium-dependent mechanism. Purines may be implicated in physiological erection in man.