C-reactive protein triggers inflammatory responses partly via TLR4/IRF3/NF-κB signaling pathway in rat vascular smooth muscle cells

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

Life Sciences, Immunology, Molecular Biology +13

Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events

Paul M. Ridker, Nader Rifai, Lynda Rose et al. · New England Journal of Medicine · 2002 · 3.6K citations · Full text

Medicine, Gynecology, High-risk Pregnancy +3

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

Life Sciences, Cell Biology, Immunology +10

Plasma Concentration of C-Reactive Protein and Risk of Developing Peripheral Vascular Disease

Paul M. Ridker, Mary Cushman, Meir J. Stampfer et al. · Circulation · 1998 · 976 citations

Medicine, Cardiology, Clinical Cardiology +15

Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation.

Kristina Edfeldt, Jesper Swedenborg, Göran K. Hansson et al. · PubMed · 2002 · 854 citations

Life Sciences, Immunology, Pathology +17