Blockade of morphine-induced analgesia and tolerance in mice by MK-801

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

Nursing, Pharmacology, Pain Management +14

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

Amy B. MacDermott, Mark L. Mayer, Gary L. Westbrook et al. · Nature · 1986 · 1.8K citations

Life Sciences, Neurobiology, Neuroscience +12

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

Keith A. Trujillo, Huda Akil · Science · 1991 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

SIMULTANEOUS QUANTITATIVE ASSESSMENT OF MORPHINE TOLERANCE AND PHYSICAL DEPENDENCE

E. Leong Way, Fu-Hsiung Shen · Journal of Pharmacology and Experimental Therapeutics · 1969 · 680 citations

Medicine, Pharmacokinetics, Pharmacology +10

Excitatory amino acids in the brain - focus on NMDA receptors

Carl W. Cotman, Leslie L. Iversen · Trends in Neurosciences · 1987 · 642 citations

Life Sciences, Neurobiology, Neuroscience +14