Angewandte Chemie International Edition · 2008 · 85 citations · 19 references
Life SciencesImmunologyMolecular BiologyBiosensorsSensorsVirologyAntigen Detection AssaysBiosensors For Immune DetectionInfectious Disease DetectionMolecular SensorsPathogen DetectionViral DiagnosticsInfluenza DiagnosticsMagnetic BiosensorsMagnetic Immunosensors
Catching the flu: Magnetic particle aggregation has been used to provide a highly sensitive, NMR-based sensor for detecting antibodies to an influenza virus. To achieve high sensitivity, a homogeneous magnetic field (H) was employed to enhance antibody-based cross-linking between particles suspended in solution (see scheme; ΔT2: change in the transverse relaxation time).
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Magnetic relaxation switches capable of sensing molecular interactions
Juan Manuel Sánchez Pérez, Lee Josephson, T. O'Loughlin et al. · Nature Biotechnology · 2002 · 892 citations · Full text
Juan Manuel Sánchez Pérez, Terence O'Loughin, F. Joseph Simeone et al. · Journal of the American Chemical Society · 2002 · 355 citations