Fixed-Dose Combination Therapy in Hypertension

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38

BMJ · 1998 · 6.7K citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +16

Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

Edmund J. Lewis, Lawrence G. Hunsicker, William R. Clarke et al. · New England Journal of Medicine · 2001 · 6K citations · Full text

Medicine, Nephrology, Pharmacology +16

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial

Lennart Hansson, Alberto Zanchetti, S. George Carruthers et al. · The Lancet · 1998 · 5.8K citations

Medicine, Pharmacology, Pharmacotherapy +12

Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

JAMA · 2002 · 5.7K citations

Medicine, Cardiology, Pharmacology +14

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38

M R Stearne, S L Palmer, M S Hammersley et al. · 1998 · 4.8K citations

Medicine, Internal Medicine, Pharmacotherapy +16