Science · 1963 · 294 citations · 8 references
Life SciencesBiochemistryCell BiologyCellular BiochemistryEnzymologySperm BiologyHeterogeneitySperm Heterogeneity
Human spermatozoa, representing a homogeneous population of postmitotic cells, contain five electrophoretically distinct lactic dehydrogenases and two malic dehydrogenases. This indicates that molecular heterogeneity of enzymes is characteristic of the individual cell and is not a reflection of heterogeneity of cell types within a tissue.
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Lactate Dehydrogenases in Human Testes
Antonio Blanco, William H. Zinkham · Science · 1963 · 320 citations
Molecular Heterogeneity and Evolution of Enzymes
Nathan O. Kaplan, Margaret M. Ciotti, Robert E. Bieber et al. · Science · 1960 · 259 citations