Life-span carcinogenicity tests with 4-amino-N10-methylpteroylglutamic acid (methotrexate) in Swiss mice and Syrian golden hamsters

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

Sidney Farber, Louis K. Diamond, Robert D. Mercer et al. · New England Journal of Medicine · 1948 · 1.8K citations

Pharmacy, Pharmacology, Pharmacotherapy +11

Effect of Methotrexate Therapy upon Choriocarcinoma and Chorioadenoma

M. C. Li, R. Hertz, David Spencer · Experimental Biology and Medicine · 1956 · 511 citations

Medicine, Oncology, Pharmacology +12

Induction of Lung Tumors and Malignant Lymphomas in Mice by Metronidazole<xref ref-type="fn" rid="FN2">2</xref>

Mario Rustia, Philippe Shubik · JNCI Journal of the National Cancer Institute · 1972 · 237 citations

Medicine, Oncology, Pharmacology +12

THE MECHANISM OF ACTION OF THE FOLATE ANTAGONISTS IN MAN.

Joseph Bertino · PubMed · 1963 · 225 citations

Life Sciences, Biochemistry, Pharmacology +13

Parenteral Methotrexate in Psoriasis

Emma Scott · Archives of Dermatology · 1964 · 163 citations

Pharmacy, Dermatology, Pharmacotherapy +10