Concepedia

Effects of phenobarbital on metabolism and toxicity of diclofenac sodium in rat hepatocytes in vitro

Ao-Hua Wang, Tao Xia, Jun‐Hui Yuan, Runze Yu, Kai-Kai Yang, X.M. Chen, Wei Qu, Michael P. Waalkes

Food and Chemical Toxicology · 2004 · 14 citations · 17 references

DOI

Concepts

References

17

Hepatocyte function and extracellular matrix geometry: long‐term culture in a sandwich configuration

James Dunn, Martin L. Yarmush, H.G. Koebe et al. · The FASEB Journal · 1989 · 737 citations

, , +16

Diclofenac-associated hepatotoxicity: Analysis of 180 cases reported to the food and drug administration as adverse reactions

Alpha Banks, Hyman J. Zimmerman, Kamal G. Ishak et al. · Hepatology · 1995 · 294 citations · Full text

, , +10

Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death

Eric Hickey, Ravindra R. Raje, Vincent E. Reid et al. · Free Radical Biology and Medicine · 2001 · 218 citations

, , +14

Drug metabolism in hepatocyte sandwich cultures of rats and humans

A. D. Kern, A. Bader, R. Pichlmayr et al. · Biochemical Pharmacology · 1997 · 187 citations

, , +12

Metabolic Activation of Diclofenac by Human Cytochrome P450 3A4:  Role of 5-Hydroxydiclofenac

Sijiu Shen, Michael R. Marchick, Margaret R. Davis et al. · Chemical Research in Toxicology · 1999 · 183 citations

, , +17