Concepedia

The combination of metallothionein and superoxide dismutase protects pancreatic β cells from oxidative damage

Leejin Park, Dongsoo Min, Hyunok Kim, Jinseu Park, Soo‐Young Choi, Yong Soo Park

Diabetes/Metabolism Research and Reviews · 2011 · 32 citations · 7 references

DOIFull text

Open access

Abstract

Transduction of Tat-MT and Tat-SOD proteins offers a new strategy for protecting against the development of diabetes by relieving oxidative stress.

References

7

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Metallothionein Inhibits Peroxynitrite-induced DNA and Lipoprotein Damage

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Proteins Linked to a Protein Transduction Domain Efficiently Transduce Pancreatic Islets

Jennifer E. Embury, Dagmar Klein, Antonello Pileggi et al. · Diabetes · 2001 · 112 citations · Full text

MnSOD and Catalase Transgenes Demonstrate That Protection of Islets From Oxidative Stress Does Not Alter Cytokine Toxicity

Hainan Chen, Xiaoyan Li, Paul N. Epstein · Diabetes · 2005 · 112 citations · Full text

HIV-1 Tat-mediated protein transduction of Cu,Zn-superoxide dismutase into pancreatic β cells in vitro and in vivo

Won Sik Eum, In Soon Choung, Ming Zhen Li et al. · Free Radical Biology and Medicine · 2004 · 89 citations

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