Recent Developments in Boron Neutron Capture Therapy (BNCT) Driven by Nanotechnology

Yinghuai Zhu, Koh Cheng Yan, John A. Maguire, Narayan S. Hosmane

Current Chemical Biology · 2007 · 67 citations · 1 references

Concepts

Abstract

Boron neutron capture therapy (BNCT) is a promising treatment for malignant brain tumors as well as other cancers. Current research centers on both the design and synthesis of high boron containing compounds as BNCT agents, and the search for more effective delivery vehicles. This review discusses recent work on the development of nanomaterial based BNCT agents. Keywords: Boron neutron capture therapy (BNCT), liposome, dendrimer, single-/multi-wall carbon nanotube (S/MWCNT), magnetic nanoparticle

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