Concepedia

Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function

Jungwook Kim, Hui Xiao, J.B. Bonanno, Chakrapani Kalyanaraman, Shoshana Brown, Xiang‐Ying Tang, Nawar Al-Obaidi, Y. Patskovsky, Patricia C. Babbitt, Matthew P. Jacobson,

Nature · 2013 · 96 citations · 35 references

Concepts

Life SciencesBiochemistryMolecular BiologyMetabolismStructural BiochemistryStructural BiologyNucleotide MetabolismRibonucleic Acid (Rna) ChemistryRna ChemistryRna StructureAminoacyl-transfer Ribonucleic Acid Synthetase StructureAminoacyl-transfer Rna Synthetase SpecificityAminoacyl-trna SynthetasesStructure-guided Lead DiscoverySubstrate Specificity Of Aminoacyl-transfer Ribonucleic Acid SynthetasesTransfer Rna (Trna) ChemistryTrna Modification Effects

References

35

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

Garib N. Murshudov, A. A. Vagin, E. J. Dodson · Acta Crystallographica Section D Biological Crystallography · 1997 · 14.9K citations

Life Sciences, Biochemistry, Biophysics +13

The Pfam Protein Families Database

Alex Bateman · Nucleic Acids Research · 2002 · 14.2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

Database resources of the National Center for Biotechnology Information: update

David Wheeler · Nucleic Acids Research · 2003 · 11K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

MUSCLE: a multiple sequence alignment method with reduced time and space complexity

R. C. Edgar · BMC Bioinformatics · 2004 · 9.4K citations · Full text

Life Sciences, Bioinformatics, Biology +13