Publication | Closed Access
(E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate: An Intermediate in the Formation of Terpenoids in Plant Chromoplasts
26
Citations
0
References
2002
Year
Plant PhysiologyEngineeringBotanyMolecular BiologySecondary MetaboliteNew Deoxyxylulose PhosphatePlant TerpenoidsCyclic Diphosphate 1Plant Molecular BiologyBiosynthesisNatural Product Biosynthesis-4-Hydroxy-3-methylbut-2-enyl DiphosphatePhotosynthesisPlant CytologyBiochemistryPlant MetabolismBiologyNatural SciencesPlant ChromoplastsPhytochemistryPlant Biochemistry
The missing link in the new deoxyxylulose phosphate metabolic pathway leading to the biosynthesis of plant terpenoids has been identified. The intermediate between the cyclic diphosphate 1 and the basic isoprenoid building blocks dimethylallyl diphosphate and isopentenyl diphosphate has been shown for the first time to be (E)-4-hydroxy-3-methylbut-2-enyl diphosphate (2) by incorporation of tritium-labeled 2 into phytoene.