Prothrombin complex concentrate (Beriplex P/N) for control of bleeding after kidney trauma in a rabbit dilutional coagulopathy model

Calibrated Automated Thrombin Generation Measurement in Clotting Plasma

H.C. Hemker, Peter Giesen, Raed Al Dieri et al. · Pathophysiology of Haemostasis and Thrombosis · 2003 · 1.4K citations · Full text

Medicine, Hematology, Good Laboratory Practice +16

Recombinant Factor VIIa as Adjunctive Therapy for Bleeding Control in Severely Injured Trauma Patients: Two Parallel Randomized, Placebo-Controlled, Double-Blind Clinical Trials

Kenneth D Boffard, Bruno Riou, Brian Warren et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2005 · 785 citations

Medicine, Pharmacotherapy, Surgery +16

The Effect of Temperature and pH on the Activity of Factor VIIa: Implications for the Efficacy of High-Dose Factor VIIa in Hypothermic and Acidotic Patients

Zhi Hong Meng, Alisa S. Wolberg, Dougald M. Monroe et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2003 · 472 citations

Medicine, Hematology, Pharmacology +17

Management of bleeding following major trauma: a European guideline

Donat R. Spahn, Vladimír Černý, Tim Coats et al. · Critical Care · 2007 · 438 citations · Full text

Medicine, Emergency Medicine, Surgery +16

Recommendations on the use of recombinant activated factor VII as an adjunctive treatment for massive bleeding – a European perspective

Jean‐Louis Vincent, Rolf Rossaint, Bruno Riou et al. · Critical Care · 2006 · 384 citations · Full text

Medicine, Perioperative Medicine, Surgery +8