Increased brain P-glycoprotein in morphine tolerant rats

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

Carlos Cordon‐Cardo, James P. O’Brien, João Paulo Boccia et al. · Journal of Histochemistry & Cytochemistry · 1990 · 1.1K citations

Medicine, Molecular Biology, Oncology +14

Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers

Laurent Salphati, Leslie Z. Benet · Biochemical Pharmacology · 1998 · 146 citations

Medicine, Biochemistry, Pharmacology +13

In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier

Atsushi Sakata, Ikumi Tamai, Kouichi Kawazu et al. · Biochemical Pharmacology · 1994 · 143 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells

Richard Callaghan, J.R. Riordan · Journal of Biological Chemistry · 1993 · 141 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Inhibition of morphine tolerance and physical dependence development and brain serotonin synthesis by cycloheximide

Horace H. Loh, Fu-Hsiung Shen, E. Leong Way · Biochemical Pharmacology · 1969 · 116 citations

Medicine, Neuroscience, Pharmacology +16