Experimental Biology and Medicine · 1962 · 108 citations · 0 references
Life SciencesEndocrinologyVeterinary PhysiologyLipid BiochemistryNeuroendocrinologyPharmacodynamicsAdipose TissueAdrenal Steroid HormonesFatty Acid ChemistryFatty Acid MetabolismLipid MetabolismAdipose Tissue LipolysisCatecholamine Regulation Of MetabolismFatty AcidsFree Fatty Acid MetabolismLinoleic Acid ContentOleic Acid ContentTissue-selective ReleaseUnsaturated Fatty Acids
SummaryThe effect of epinephrine and norepinephrine on the individual free fatty acids of plasma was investigated in anesthetized dogs. The increased arterial FFA after administration of catecholamines was due to a rise in concentration of most major fatty acids. The percentage contribution of oleic and linoleic acids to total arterial FFA was also increased. A direct relationship was found, both in normal and in diabetic dogs, between the resting arterial FFA level and percentage of oleic acid in FFA. An attempt was made to relate these findings to the selective release of FFA from adipose tissue that occurs in the normal animal.