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Genome-inspired search for new antibiotics. Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34

Antimicrobial Drug DiscoveryAntimicrobial Resistance GeneStreptomyces Halstedii Hc34AntibioticsGenome-inspired SearchStructure DeterminationMolecular BiologySynthetic BiologyMicrobiologyAntimicrobial CompoundAntibiotic ResistanceMedicineAntimicrobial ResistanceMicrobial Genetics