Concepedia

Mesenchymal Stem Cells Enhance Allogeneic Islet Engraftment in Nonhuman Primates

Dora M. Berman, Melissa A. Willman, Dongmei Han, Gary Kleiner, Norman M. Kenyon, Over Cabrera, Julie A. Karl, Roger W. Wiseman, David H. O’Connor, Amelia Bartholomew,

Diabetes · 2010 · 201 citations · 40 references

DOI

Abstract

MSCs may provide an important approach for enhancement of islet engraftment, thereby decreasing the numbers of islets needed to achieve insulin independence. Furthermore, MSCs may serve as a new, safe, and effective antirejection therapy.

References

40

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Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy · 2006 · 17.4K citations

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Human mesenchymal stem cells modulate allogeneic immune cell responses

Sudeepta Aggarwal, Mark F. Pittenger · Blood · 2004 · 4.5K citations · Full text

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

Massimo Di Nicola, Carmelo Carlo‐Stella, Michele Magni et al. · Blood · 2002 · 3.2K citations · Full text

Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

Amelia Bartholomew, Cord Sturgeon, Mandy Siatskas et al. · Experimental Hematology · 2002 · 2.3K citations · Full text

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