Circulation · 1969 · 18 citations · 0 references
MedicineCardiologySurgeryCardiothoracic SurgeryClinical CardiologyHemodynamic ManagementCardiac Valve SurgeryHeart FailureMitral Valve DiseasePerioperative Hemodynamic ManagementSurgical Valve ReplacementThoracic SurgeryCardiac IndexMitral Valve HemodynamicsPulmonary Vascular Resistance AssessmentPulmonic Valve ProsthesisRight Heart HemodynamicsSurgical Mitral Valve ReplacementVascular Resistance
The first 21 survivors of mitral valve replacement with a Beall valve prosthesis were evaluated clinically and hemodynamically five months after surgery. Significant clinical improvement was noted in 18 of 21 patients. When compared with preoperative data, a significant improvement occurred in pulmonary artery and left atrial pressures, cardiac index, pulmonary vascular resistance, and in the mitral valve gradient. However, the majority of the patients still had mildly elevated left atrial and pulmonary artery pressures secondary to a mean resting prosthetic gradient of 7 mm Hg. Right heart pacing and exercise significantly increased the gradient and left atrial and pulmonary artery pressures. A remarkable freedom from thromboembolic complications was noted in this series of patients.