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Taxol and Derivatives: A Biogenetic Hypothesis
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1987
Year
Bioorganic ChemistryGeneticsSecondary MetaboliteChemical BiologyEpigeneticsMedicinal ChemistryBiosynthesisBiochemical TaxonomyBiogenetic HypothesisComplex MoleculeStructural DifferencesBiogenetic ApproachBiochemistryPharmacologyNatural Product SynthesisNatural SciencesGenetic MechanismPhytochemistryMedicineChemotaxonomy
Based on the structural differences of compounds isolated from various species of Taxus, this brief review suggests a biogenetic approach to taxol. This hypothesis could be of some help in the synthesis of this complex molecule exhibiting significant antitumor properties.