Synthesis of Coumarins in a Molten <i>n‐</i>Bu₄NOAc/<i>n</i>‐Bu₄NBr Mixture through a Domino Heck Reaction/Cyclization Process

Abstract

Abstract 4‐Arylcoumarins can be prepared in good to high yields by reacting readily available methyl or butyl 3‐( o ‐hydroxyaryl)acrylates with aryl iodides and bromides in an n ‐Bu 4 NOAc/ n ‐Bu 4 NBr mixture at 100 °C in the presence of Pd(OAc) 2 .