Concepedia

Sevoflurane Preconditioning Limits Intracellular/Mitochondrial Ca2+ in Ischemic Newborn Myocardium

Hong Liu, Lianguo Wang, Matt Eaton, Saul Schaefer

Anesthesia & Analgesia · 2005 · 22 citations · 24 references

Open access

Abstract

The results of this study support the hypothesis that sevoflurane preconditioning protects newborn hearts from calcium overload and ischemic injury via a mechanism dependent on mitochondrial KATP channels.

References

24

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M Tani, J. R. Neely · Circulation Research · 1989 · 758 citations

Cardiac Muscle, Heart Failure, Cardiovascular Function +18

Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart.

Charles Steenbergen, Elizabeth Murphy, L Lévy et al. · Circulation Research · 1987 · 499 citations

Myocardial Ischemia, Cardiac Muscle, Heart Failure +18

Isoflurane Mimics Ischemic Preconditioning via Activation of KATPChannels

Judy R. Kersten, Todd J. Schmeling, Paul S. Pagel et al. · Anesthesiology · 1997 · 422 citations · Full text

ATP‐sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria

Ekhson Holmuhamedov, Liewei Wang, André Terzic · The Journal of Physiology · 1999 · 344 citations · Full text

Cardiac Muscle, Rat Cardiac Mitochondria, Heart Failure +26

Ischemic preconditioning in rats: role of mitochondrial KATPchannel in preservation of mitochondrial function

Ryan M. Fryer, Janis T. Eells, Anna K. Hsu et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2000 · 224 citations