Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 20.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

Michael W. Pfaffl · Nucleic Acids Research · 2002 · 7.4K citations · Full text

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Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

Claus L. Andersen, Jens Ledet Jensen, Torben F. Ørntoft · Cancer Research · 2004 · 7.2K citations

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A microRNA component of the p53 tumour suppressor network

Lin He, Xingyue He, Lee P. Lim et al. · Nature · 2007 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +14

Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis

Tsung-Cheng Chang, Erik A. Wentzel, Oliver A. Kent et al. · Molecular Cell · 2007 · 2K citations · Full text

Life Sciences, Genetics, Molecular Biology +14