Thiazolsynthesen mit <i>N</i>‐Cyanimidsäureestern oder 3‐Cyanisoharnstoffen und Thioglycolsäurederivaten

Abstract

Thiazoles from N ‐Cyanoimidates or 3‐Cyanoisoureas and Thioglycolic Acid Derivatives Novel thiazoles 3a – g , 4a – d are synthesized from N ‐cyanoimidates and 3‐cyanoisoureas of type 1a – m and thioglycolic acid methyl ester ( 2a ) as well as the amide ( 2b ). The limitations of the reaction are outlined. The products are further converted into thiazolo[4,5‐ d ]pyrimidines 6a – d and thiazolo [4,5‐ d ]‐1,2,3‐triazinones 7a – c .