Publication | Closed Access
New Activators for the Coupling Reaction of Terminal Alkynes with Organic Halides
13
Citations
47
References
2005
Year
Chemical EngineeringCross-coupling ReactionEngineeringOrganic HalidesAlkene MetathesisNew ActivatorsCoupling ReactionOrganic ChemistryOrganometallic CatalysisCatalysisChemistryAbstract Cross-coupling ReactionsBiomolecular EngineeringCoupling Products
Abstract Cross-coupling reactions of terminal alkynes with organic halides catalyzed by palladium(0) or palladium(0)/Cu(I) take place in the presence of several activators, such as silver(I) oxide, tetrabutylammonium fluoride (TBAF), and tetrabutylammonium hydroxide (TBAOH), to give the corresponding coupling products in good-to-excellent yields.
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