Journal of the European Academy of Dermatology and Venereology · 2006 · 11 citations · 20 references
Life SciencesImmunologyInfectious DiseasesAutoimmunityHepatologyImmunopathologyAntiviral TherapyAutoimmune DiseasesAutoimmune Skin DiseasesInterferon-based TherapyLiver DiseaseViral HepatitisHepatitis C InfectionImmunomodulatory EffectsInterferon Alfa TherapyInterferon-mediated Pathology
A patient with hepatitis C virus (HCV) infection was diagnosed with cutaneous, pulmonary and hepatic sarcoidosis following interferon alpha therapy. There are only a few cases of sarcoidosis associated with this treatment. This is the first case who not only developed sarcoidosis, but also autoimmune hypothyroidism and thrombocytopenia during interferon alpha therapy due to the immunomodulatory effects of the drug.
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Side effects of high-dose interferon therapy for chronic hepatitis C
T Okanoue, Shinichi Sakamoto, Yoshito Itoh et al. · Journal of Hepatology · 1996 · 463 citations
Bruce Robinson, Theodore L. McLemore, Ronald G. Crystal · Journal of Clinical Investigation · 1985 · 462 citations · Full text
Exacerbation of symptoms of autoimmune disease in patients receiving alpha-interferon therapy
Kevin C. Conlon, Walter J. Urba, John W. Smithii et al. · Cancer · 1990 · 298 citations