Amplification and characterization of a β-globin gene synthesized in vitro

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

A complementation analysis of the restriction and modification of DNA in Escherichia coli

Herbert W. Boyer, Daisy Roulland-Dussoix · Journal of Molecular Biology · 1969 · 3.9K citations

Life Sciences, Genetics, Microbiology +11

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

Phillip A. Sharp, Bill Sugden, Joe Sambrook · Biochemistry · 1973 · 1.6K citations

Life Sciences, Biochemistry, Microbiology +12

Nature of Col E ₁ Plasmid Replication in <i>Escherichia coli</i> in the Presence of Chloramphenicol

Don B. Clewell · Journal of Bacteriology · 1972 · 1.2K citations · Full text

Life Sciences, Genetics, Microbiology +13

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

Richard R. Burgess, Jerome J. Jendrisak · Biochemistry · 1975 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +8