Reduction of Tissue Plasminogen Activator-Induced Matrix Metalloproteinase-9 by Simvastatin in Astrocytes - Concepedia

Concepedia

Publication | Closed Access

Reduction of Tissue Plasminogen Activator-Induced Matrix Metalloproteinase-9 by Simvastatin in Astrocytes

68

Citations

12

References

2006

Year

Sophia Y. Wang, Sun-Ryung Lee, Shuzhen Guo, Woo Jean Kim, Joan Montaner, Xiaoying Wang, Eng H. Lo

Abstract

Statins reduce tPA-induced MMP-9 dysregulation by inhibiting the Rho signaling pathway. Statins may ameliorate tPA-associated MMP imbalances in stroke.

References

	Year	Citations

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