Concepedia

Efficient Proline-Catalyzed Michael Additions of Unmodified Ketones to Nitro Olefins

Benjamin List, Peter Pojarliev, Harry J. Martin

Organic Letters · 2001 · 587 citations · 11 references

DOI

Concepts

Abstract

[reaction: see text] Here we describe the proline-catalyzed Michael addition of unmodified ketones to nitro olefins. This novel reaction provides gamma-nitro ketones in modest enantioselectivity yet excellent yields.

References

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