Gene–environment interaction between adiponectin gene polymorphisms and environmental factors on the risk of diabetic retinopathy

Abstract

No significant association was identified between four adiponectin polymorphisms and DR susceptibility after stringent Bonferroni correction. The interaction between C-11377G (rs266729) polymorphism and insulin therapy, as well as the interaction between family history of diabetes and insulin therapy, might be associated with DR susceptibility.