INCREASED TYROSINE HYDROXYLASE IMMUNOREACTIVITY IN BLADDER TISSUE FROM PATIENTS WITH CLASSIC AND NONULCER INTERSTITIAL CYSTITIS

Abstract

Our findings indicate an altered peripheral sympathetic innervation in interstitial cystitis cases, which may be an indication of primary neurogenic etiology. The difference in nerve density observed after incubation with the antibody mixture between classic and nonulcer interstitial cystitis supports the hypothesis that the 2 forms represent separate entities.