Efficient Stereospecific Syntheses of Chiral Ruthenium Dimers

Abstract

The stereospecific synthesis of three isomeric Ru dimers, Δ,Δ-[(phen)2Ru(tpphz)Ru(phen)2]4+ (Δ,Δ-4) (where tpphz = tetrapyrido[3,2-a:2‘,3‘-c:3‘‘,2‘‘-h:2‘‘,3‘‘-j]phenazine), Λ,Λ-4, and Λ,Δ-4, can be accomplished in high yield with retention of optical activity by the formation of a phenazine ring between appropriately functionalized chiral precursors.