Severe Seizures During Propofol Induction in a Patient with Syringomyelia Receiving Baclofen

Abstract

We report the occurrence of recurrent severe generalized seizures during induction of anesthesia with propofol in a patient with syringomyelia receiving baclofen for flexor spasms undergoing neurosurgery. We discuss the possible epileptogenic interaction between baclofen and propofol in our patient.