The synthesis and structure of {[PimPri,But ]ZnOH}(ClO4): a tris(imidazolyl)phosphine zinc hydroxide complex and a proposed structural model for carbonic anhydrase

Abstract

The zinc hydroxide complex {[Pimpri,But]ZnOH}(ClO4) is synthesized by the reaction of [Pimpri,But] with Zn(ClO4)2·6H2O; {[Pimpri,But]ZnOH}(ClO4) is the first structurally characterized monomeric zinc hydroxide complex supported by imidazole functionalities and is therefore an excellent structural model for the active site of carbonic anhydrase.