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Antiinflammatory Activity of 3 β-Hydroxy-2,3-dihydro-withanolide F
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1984
Year
Sub-acute InflammationPharmacotherapyPharmaceutical ChemistryOxidative StressNeuroinflammationInflammationMedicinal ChemistryNeuroimmunologyAnti-inflammatory ActivityAllergyBiochemistryMechanism Of ActionPharmacological AgentPharmacologyWeight BasisAnti-inflammatoryNatural SciencesInflammation BiologyMedicineDrug Discoveryβ-Hydroxy-2,3-dihydro-withanolide F
Anti-inflammatory activity of 3β-hydroxy-2,3-dihydro-withanolide F has been assessed and it was found to possess marked effects in sub-acute inflammation. A comparison of the anti-inflammatory properties showed that it is approximately 5 times more active than phenylbutazone and equally active to that of hydrocortisone on weight basis. The withanolide did not exhibit any effect on CNS.