Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance

Publication | Open Access

DOI Full Paper Access

Citations

References

2012

Year

Fabrizio Giordanetto, Andreas Wållberg, Saswati Ghosal, Tommy Iliefski, Johan Cassel, Zhong-Qing Yuan, Henrik von Wachenfeldt, Søren Andersen, Tord Inghardt, Anders Tunek,

Bioorganic & Medicinal Chemistry Letters

Insulin ResistanceMolecular PharmacologyPhosphoinositide 3-KinasesIsoform InhibitorBiochemistryMedicinePharmacological AgentPharmacotherapyPlatelet AntagonistPharmacologyDrug DiscoveryTranslational Pharmacology