Value of fine needle aspiration cytology in head and neck lymphoma: Experience in a head and neck cancer unit in the United Kingdom

Abstract

A total of 121 cases met the inclusion criteria. The FNAC diagnosis of lymphoma was correct on lymph node biopsy in 68.6% (83/121). In 18 (14.9%) cases a false-negative result and in 3 (2.5%) cases a false-positive result was seen. In all, 17 (14.0%) cases were non-diagnostic (11 inadequate and 6 suspicious). In 16/20 (80.0%) cases of wrong diagnosis, immunocytochemistry had not been performed. Flow cytometry and immunocytochemistry were used in 67 cases and the FNAC diagnosis had a sensitivity of 95.5% and a PPV of 96.8% in this group.