The action of nitric oxide in the perfused human fetal-placental circulation

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Endothelium‐derived relaxing and contracting factors

Robert F. Furchgott, Paul M. Vanhoutte · The FASEB Journal · 1989 · 2K citations

Life Sciences, Pharmacology, Physiology +13

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Life Sciences, Biophysics, Physiology +6

Flow-induced release of endothelium-derived relaxing factor

Gabor M. Rubanyi, J. C. Romero, PM Vanhoutte · American Journal of Physiology-Heart and Circulatory Physiology · 1986 · 1.4K citations

Medicine, Cardiology, Pharmacology +13

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

William Martin, G. Villani, D Jothianandan et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 1.3K citations

Medicine, Pharmacology, Physiology +8