NOD2/CARD15 Genotype and Phenotype Differences between Ashkenazi and Sephardic Jews with Crohn's Disease

Abstract

NOD2/CARD15 CD-associated mutations confer increased risk mainly to the Ashkenazi Jewish CD patients in Israel. This suggests that NOD2/CARD15 mutations could contribute to the higher incidence and prevalence rates of CD among Ashkenazi Jews.