Feasibility of Three-Dimensional Optical Coherence Tomography and Optical Doppler Tomography of Malignancy in Hamster Cheek Pouches

Abstract

OCT imaging offered exceptional resolution of the HCP to depths of 1-2 mm and confirmed ability to detect dysplasia and malignancy. Three-dimensional OCT images were readily constructed, allowing visualization of extent and localization of tumor margins. ODT demonstrated increased vascularity in the area of neoplasia. OCT/ODT is a promising new technology for oral airway diagnostics.