Al‐Catalyzed Facile Construction of Quaternary CC Bonds by the Allylic Substitution of Tertiary Alcohols: A Concise and Formal Synthesis of (±)‐Mersicarpine

Abstract

In close quarters: A concise, high-yielding, and more sustainable route for the synthesis of (±)-mersicarpine in nine linear steps from commercially available indole and succinic anhydride is presented (see scheme). It is also demonstrated that the novel protocol can be commonly used for the rapid and flexible construction of a diverse class of mersicarpine analogues. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.