Second Sphere Coordination Adducts of Phosphane‐Transition Metal Complexes with β‐Cyclodextrin and its Methylated Derivative

Abstract

In the formation of the βCD·1 adduct (shown on the right), the complex trans-[Pt(PMe3)Cl2(NH3)] 1 inserts its hydrophobic PMe3 ligand into the narrow opening of the β-cyclodextrin (βCD) cavity, as has been shown by an X-ray structure analysis. The neutral complex is bound only by βCD, but not by αCD. This finding is of interest with regard to the development of water-soluble catalysts and drug delivery systems.