Azotemia and Glucose Intolerance

Abstract

Article1 June 1967Azotemia and Glucose IntoleranceJAMES M. CERLETTY, M.D., NORMAN H. ENGBRING, M.D.JAMES M. CERLETTY, M.D.Search for more papers by this author, NORMAN H. ENGBRING, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-6-1097 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe occurrence of glucose intolerance in patients with renal failure has been known for 50 years (1-3); however, the cause of this impaired tolerance is not yet established. Perkoff and colleagues (4) suggested that urea may have a specific effect on glucose metabolism in uremia. They reported a decreased rate of glucose disappearance from the blood of normal subjects fed urea for several days but were unable to detect any influence of urea on the uptake of glucose by rat diaphragm in vitro. Sagild (5) reported that glucose tolerance in patients with acute renal failure was abnormal and that it...References1. HAMMANHIRSCHMAN LII: Studies on blood sugar. Arch. Intern. Med. (Chicago) 20: 761, 1917. CrossrefGoogle Scholar2. WILLIAMSHUMPHREYS JREM: Clinical significance of blood sugar in nephritis and other diseases. Arch. Intern. Med. (Chicago) 23: 537, 1919. CrossrefGoogle Scholar3. LINDERHILLERVANSLYKE GCADD: Carbohydrate metabolism in nephritis. J. Clin. Invest. 1: 247, 1925. CrossrefMedlineGoogle Scholar4. PERKOFFTHOMASNEWTONSELLMANTYLER GTCLJDJCFH: Mechanism of impaired glucose tolerance in uremia and experimental hyperazotemia. Diabetes 7: 375, 1958. CrossrefMedlineGoogle Scholar5. SAGILD U: Glucose tolerance in acute ischemic renal failure. Acta Med. Scand. 172: 405, 1962. CrossrefMedlineGoogle Scholar6. WESTERVELTSCHREINER FBGE: The carbohydrate intolerance of uremic patients. Ann. Intern. Med. 57: 266, 1962. LinkGoogle Scholar7. 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CERLETTY, M.D.; NORMAN H. ENGBRING, M.D.Affiliations: Milwaukee, WisconsinFrom the Department of Medicine, Marquette University School of Medicine and the Milwaukee County General Hospital, Milwaukee, Wis.This work was supported in part by grants 2 T1 AM 5023 and 5 M01 FR 00058-05, the U. S. Public Health Service, Washington, D. C.Requests for reprints should be addressed to James M. Cerletty, M.D., Milwaukee County General Hospital, 8700 W. Wisconsin Ave., Milwaukee, Wis. 53226. 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Plasma Growth Hormone, Insulin and Glucagon after Oral and Intravenous Glucose in Uremic SubjectsMetabolism of xylitol in healthy subjects and patients with renal diseaseLack of dialyzable insulin antagonist in uremiaGlucose intolerance in uraemiaWHAT IS DIABETES MELLITUS?GLYCOGEN CONTENT OF SKELETAL MUSCLE IN PATIENTS WITH RENAL FAILUREThe Renal Excretion of Nitrogen Containing MetabolitesCarbohydrate metabolism studies in cirrhosis of the liverMedical management of chronic renal failureUntersuchungen zur urämischen KohlenhydratstoffwechselstörungCarbohydrate Metabolism in UremiaEDWARD S. HORTON, M.D., CHARLES JOHNSON, M.D., HAROLD E. LEBOVITZ, M.D. 1 June 1967Volume 66, Issue 6Page: 1097-1108KeywordsGlucoseGlucose intoleranceGlucose metabolismGlucose toleranceHospital medicineImmunoassaysInsulinMedical servicesRenal failureUrea ePublished: 1 December 2008 Issue Published: 1 June 1967 PDF downloadLoading ...